Description

D-[2-2H]Galactose is a stable isotope-labeled analog of the essential monosaccharide D-galactose, specifically deuterated at the 2-position. This compound is a critical tool for metabolic pathway tracing and quantitative analysis in biochemical and pharmaceutical research. It is primarily utilized by research scientists and process developers in the life sciences, pharmaceutical development, and analytical chemistry sectors who require precise isotopic labeling for mass spectrometry-based studies.

Application

• Metabolic Flux Analysis (MFA): Used as a stable isotope tracer to study galactose metabolism, glycolysis, and related pathways in cell cultures and biological systems.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS/MS and GC-MS for the accurate quantification of galactose and its metabolites in biological matrices.
• Biochemical Research: Enables detailed investigation into congenital disorders of glycosylation (CDG) and other inborn errors of galactose metabolism.
• Pharmaceutical Development: Employed in the development and validation of diagnostic assays and in the study of drug effects on carbohydrate metabolic networks.
• Nutritional Science: Facilitates studies on galactose absorption, utilization, and its role in human nutrition and lactose intolerance.

Basic Information

Product Name	D-[2-2H]Galactose
CAS No.	64429-86-3
Molecular Formula	C6H11DO6
Molecular Weight	181.16 g/mol (for monoisotopic mass)
Synonyms	Deuterated D-Galactose; D-Galactose-2-d; (2R,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal-2-d; Galactose-d1; [2-2H]Galactose; 2-Deuterio-D-galactose; D-Galactose (2-2H); Stable Isotope Labeled Galactose
EINECS	Contact for details

Quality Control

Our D-[2-2H]Galactose is manufactured under strict quality systems to ensure high isotopic and chemical purity for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR and Mass Spectrometry to confirm the site-specific deuterium incorporation and overall purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 98 atom % 2H
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.