Description

Oxycodone Terephthalate (Salt) is a specific pharmaceutical salt form of the potent opioid analgesic oxycodone. This compound is critical for ensuring the stability, bioavailability, and controlled formulation of the active pharmaceutical ingredient. It is primarily required by advanced pharmaceutical manufacturers and research institutions engaged in the development and production of controlled-release pain management medications and analytical reference standards.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of finished dosage forms of oxycodone.
• Controlled-Release Formulations: Used in the development and manufacturing of extended-release tablets and capsules for chronic pain management.
• Analytical Reference Standard: Serves as a high-purity certified standard for quality control (QC) and research & development (R&D) laboratories for HPLC, LC-MS, and other analytical methods.
• Preclinical & Clinical Research: Utilized in pharmacological studies, metabolic research, and clinical trial material (CTM) production.
• Generic Drug Manufacturing: Essential for companies producing bioequivalent generic versions of oxycodone-based medications.

Basic Information

Product Name	Oxycodone Terephthalate (Salt)
CAS No.	64336-55-6
Molecular Formula	C18H21NO4 • C8H6O4
Molecular Weight	547.55 g/mol
Synonyms	Oxycodone Terephthalate; 14-Hydroxydihydrocodeinone Terephthalate; Oxycodone Hydrogen Terephthalate; Oxycodone Biterephthalate; (5R,9R)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Terephthalate; Oxycodone TPA Salt; Oxycodone Acid Terephthalate Salt; Oxycodone 1,4-Benzenedicarboxylate
EINECS	Contact for details

Quality Control

Our Oxycodone Terephthalate (Salt) is manufactured under strict quality systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and composition, aligning with ICH guidelines. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from advanced analytical techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.