Description

4-Bromogramine is a specialized brominated alkaloid derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive bromine handle on the gramine scaffold, enabling selective functionalization for the construction of complex nitrogen-containing molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry research targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the gramine moiety can contribute to biological activity.
• Organic Synthesis Reagent: Employed in various organic transformations, including alkylation and cross-coupling reactions, to introduce functionalized indole derivatives.
• Biochemical Research: Acts as a precursor or probe in biochemical studies investigating enzyme inhibition or receptor-ligand interactions.
• Material Science: Potential intermediate for synthesizing specialized polymers or organic electronic materials with unique optoelectronic properties.

Basic Information

Product Name	4-Bromogramine
CAS No.	64258-88-4
Molecular Formula	C11H13BrN2
Molecular Weight	253.14 g/mol
Synonyms	1-(3-(Dimethylamino)methyl)-4-bromo-1H-indole; 4-Bromo-3-(dimethylaminomethyl)indole; 4-Bromo-gramine; 4-Bromo-N,N-dimethyltryptamine precursor; 4-Bromogramine; Gramine, 4-bromo-; 4-Br-Gramine
EINECS	Contact for details

Quality Control

Our 4-Bromogramine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets high-purity standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.