Description

Dl-Phenylalanine-Carboxy-13C CAS NO 64193-00-6 is a stable isotope-labeled analog of the amino acid phenylalanine, specifically labeled with carbon-13 at the carboxy position. This compound is a critical tool for advanced research and development, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and nutritional research sectors who require high-fidelity isotopic labels for mass spectrometry, NMR spectroscopy, and clinical diagnostic applications.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism in cell cultures, tissues, and microorganisms.
• Quantitative Proteomics & Biomarker Discovery: Serves as a precursor for the synthesis of isotopically labeled peptides and proteins for accurate mass spectrometry-based quantification.
• Drug Metabolism and Pharmacokinetics (DMPK): Employed as an internal standard for the precise LC-MS/MS analysis of phenylalanine and related drug metabolites in biological fluids.
• Nutritional Research: Utilized in clinical studies to investigate protein synthesis, turnover, and amino acid metabolism in humans and animals.
• Synthesis of Labeled Compounds: Acts as a key building block for the preparation of more complex carbon-13 labeled pharmaceuticals, agrochemicals, and biochemicals.
• NMR Spectroscopy: Provides a non-radioactive, stable isotopic label for structural and dynamic studies of biomolecules.

Basic Information

Product Name	Dl-Phenylalanine-Carboxy-13C
CAS No.	64193-00-6
Molecular Formula	C9H1113CNO2
Molecular Weight	~166.19 g/mol (for 13C labeled form)
Synonyms	DL-Phenylalanine-1-13C; (RS)-2-Amino-3-phenylpropionic acid-1-13C; Phenylalanine-1-13C (racemic); (±)-2-Amino-3-phenylpropanoic-1-13C acid; DL-α-Amino-β-phenylpropionic acid-1-13C; 3-Phenylalanine-1-13C; (rac)-Phenylalanine-1-13C
EINECS	Contact for details

Quality Control

Our Dl-Phenylalanine-Carboxy-13C is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high isotopic and chemical purity, meeting the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) are provided, detailing specifications for isotopic enrichment, chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with relevant guidelines for the use of labeled compounds in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.