Description

1-Butanol-4,4,4-D3 is a deuterated isotopologue of n-butanol, where three hydrogen atoms at the terminal methyl group are replaced by deuterium. This compound is a critical stable isotope-labeled standard, essential for ensuring accuracy and traceability in advanced analytical techniques. It is primarily required by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard in quantitative NMR (qNMR), mass spectrometry, and metabolic studies.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS, LC-MS, and qNMR for precise quantification of organic compounds.
• Metabolic Pathway Tracing: Serves as a deuterium-labeled tracer in biochemical and pharmacological research to study drug metabolism and biological pathways.
• Pharmaceutical Impurity Profiling: Employed in method development and validation for the accurate detection and measurement of process-related impurities.
• Polymer and Material Science Research: Acts as a labeled reagent or solvent in mechanistic studies of polymerization and material synthesis.
• Environmental Analysis: Utilized as a standard in the analysis of environmental pollutants and contaminants for improved detection reliability.
• NMR Solvent and Shift Reference: Can be used in deuterated solvent mixtures or as a chemical shift reference compound in complex NMR experiments.

Basic Information

Product Name	1-Butanol-4,4,4-D3
CAS No.	64156-70-3
Molecular Formula	C4H7D3O
Molecular Weight	77.13 g/mol
Synonyms	Butan-1-ol-4,4,4-d3; n-Butanol-d3 (terminal); 1-Butanol-d3; Butyl Alcohol-d3; 1-Hydroxybutane-4,4,4-d3; n-Butyl Alcohol-d3; Deuterated n-Butanol; Butanol-4,4,4-d3
EINECS	Contact for details

Quality Control

Our 1-Butanol-4,4,4-D3 is produced and handled under strict quality management protocols. Each batch is characterized using advanced spectroscopic and chromatographic methods, including NMR, GC-MS, and HPLC, to ensure isotopic purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residue levels is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flames. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain purity and prevent isotopic exchange.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.