Description

[2R,(-)]-1,2,3,4-Tetrahydro-1-[(4-Hydroxyphenyl)Methyl]-7-Methoxy-2-Methyl-8-Isoquinolinol is a high-purity chiral isoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block or intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates targeting neurological or cardiovascular disorders.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Used as an analytical standard for method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Potential tool compound for studying enzyme interactions or receptor binding assays due to its specific stereochemistry and functional groups.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	[2R,(-)]-1,2,3,4-Tetrahydro-1-[(4-Hydroxyphenyl)Methyl]-7-Methoxy-2-Methyl-8-Isoquinolinol
CAS No.	64091-05-0
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	(-)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2-methyl-8-isoquinolinol; (2R)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2-methyl-8-isoquinolinol; (R)-(-)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2-methyl-8-isoquinolinol; 1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2-methyl-8-isoquinolinol, (2R)-; 8-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2-methyl-, (2R)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and batch-to-batch consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.