Description

1H,12H-Benzo(F)(1,3)Thiazino(2,3-A)Isoquinolin-2(3H)-One, 4,11-Dihydro -, (S)- is a high-purity, chiral organic compound belonging to the benzo-thiazino-isoquinolinone class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its specific stereochemistry and complex heterocyclic structure, which are essential for synthesizing active pharmaceutical ingredients (APIs) with targeted biological activity. This product is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of novel therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce the (S)-configured stereocenter into more complex molecules, ensuring correct pharmacological activity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a potential electron-transport or emissive layer component due to its rigid, conjugated structure.
• Ligand for Catalysis: Can be derivatized to create novel ligands for transition metal-catalyzed reactions in fine chemical production.

Basic Information

Product Name	1H,12H-Benzo(F)(1,3)Thiazino(2,3-A)Isoquinolin-2(3H)-One, 4,11-Dihydro -, (S)-
CAS No.	64059-71-8
Molecular Formula	C₁₈H₁₃NO₂S
Molecular Weight	307.37 g/mol
Synonyms	(S)-4,11-Dihydro-1H,12H-benzo[f][1,3]thiazino[2,3-a]isoquinolin-2(3H)-one; (S)-Benzo[f][1,3]thiazino[2,3-a]isoquinolin-2-one derivative; (S)-BTIQ; (S)-enantiomer of CAS 64059-71-8; 1H,12H-Benzo[f][1,3]thiazino[2,3-a]isoquinoline-2(3H)-one, 4,11-dihydro-, (S)-; 4,11-Dihydro-1H,12H-benzo[f][1,3]thiazino[2,3-a]isoquinolin-2(3H)-one, (S)-; Light-sensitive benzo-thiazino-isoquinolinone
EINECS	Contact for details

Quality Control

Our 1H,12H-Benzo(F)(1,3)Thiazino(2,3-A)Isoquinolin-2(3H)-One, 4,11-Dihydro -, (S)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D and GMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.