Description

Phenol-3,5-D2 is a deuterated derivative of phenol, where two hydrogen atoms at the 3 and 5 positions are replaced by deuterium (D), a stable hydrogen isotope. This isotopic labeling is critical for advanced analytical and research applications, providing a non-radioactive tracer with distinct spectroscopic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications such as metabolic studies, reaction mechanism elucidation, and as an internal standard in mass spectrometry.

Application

• NMR Spectroscopy: Used as a solvent or internal standard in deuterium NMR studies due to its distinct chemical shift.
• Mass Spectrometry Internal Standard: Serves as a crucial, isotopically labeled internal standard for the accurate quantification of phenol and related compounds via GC-MS or LC-MS.
• Mechanistic & Metabolic Studies: Acts as a stable isotopic tracer to investigate reaction pathways in organic synthesis and metabolic pathways in biological systems.
• Pharmaceutical Research: Employed in the development and analysis of deuterated drug candidates, where deuterium incorporation can alter pharmacokinetic properties.
• Polymer & Material Science: Used in studies of polymerization mechanisms and the analysis of polymer structures where phenol derivatives are involved.
• Chemical Reference Standard: Provides a high-purity reference material for calibrating analytical instruments and validating methods.

Basic Information

Product Name	Phenol-3,5-D2
CAS No.	64045-87-0
Molecular Formula	C6H4D2O
Molecular Weight	112.13 g/mol
Synonyms	Phenol-d2 (3,5); 3,5-Dideuterophenol; Phenol-3,5-d2; Deuterated Phenol (3,5-); Hydroxybenzene-3,5-d2; 1-Hydroxy-3,5-dideuterobenzene; [3,5-2H2]Phenol; Benzenol-3,5-d2
EINECS	Contact for details

Quality Control

Our Phenol-3,5-D2 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high isotopic purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D atom %), chemical purity, and impurity profile. We support research and industrial standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as oxidizing agents and bases. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D atom %)	≥ 98.0% (at 3,5 positions)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.