Description

4-[(R)-2-(Butylmethylamino)-1-Hydroxyethyl]-1,2-Benzenediol is a chiral, synthetic catecholamine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral intermediate or building block for the synthesis of more complex, optically active drug molecules, particularly in the adrenergic receptor modulator class. It is essential for R&D chemists and process development scientists working in the pharmaceutical and fine chemical industries who require high-purity, stereochemically defined intermediates to ensure the efficacy and safety of final active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel β-adrenergic receptor agonists and antagonists.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new cardiovascular or respiratory medications.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective chemical reactions to introduce the (R)-configured amino alcohol moiety.
• Biochemical Research: Utilized as a reference standard or probe in studies investigating catecholamine pathways and receptor binding.
• Process Chemistry: Serves as a critical intermediate in scaling up the production of specialized drug candidates from laboratory to pilot plant scale.

Basic Information

Product Name	4-[(R)-2-(Butylmethylamino)-1-Hydroxyethyl]-1,2-Benzenediol
CAS No.	64037-63-4
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	(R)-4-[2-(Butylmethylamino)-1-hydroxyethyl]benzene-1,2-diol; (R)-N-Butyl-N-methyl-3,4-dihydroxyphenylethanolamine; (R)-Butylmethylaminoethylcatechol; (R)-BMEC; Ritalinic acid intermediate (related); AR-R15896AR (possible research code); Adrenergic β-agonist intermediate
EINECS	Contact for details

Quality Control

Our 4-[(R)-2-(Butylmethylamino)-1-Hydroxyethyl]-1,2-Benzenediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.