Description

(+)-Pentazocine Mixed Agonist/Antagonist is a high-purity, single-enantiomer pharmaceutical active ingredient with the CAS registry number 64024-15-3. This compound is a critical intermediate and reference standard in the research and development of novel analgesic and central nervous system (CNS) active pharmaceutical ingredients (APIs). It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions focused on pain management, neuropharmacology, and receptor interaction studies.

Application

• Pharmaceutical R&D: Serves as a key chiral intermediate in the synthesis of advanced analgesic drugs and as a reference standard for method development and validation.
• Analgesic Research: Used in preclinical and clinical studies to investigate mixed agonist/antagonist activity at opioid receptors for pain relief with reduced abuse potential.
• Reference Standard: Employed in analytical laboratories for quality control (QC) and quality assurance (QA) testing of pharmaceutical products containing pentazocine or related compounds.
• Neuropharmacology Studies: Utilized in research to study the mechanisms of action, pharmacokinetics, and pharmacodynamics of synthetic opioid analgesics.
• Process Chemistry: Acts as a starting material or intermediate for the scalable synthesis of specialized pharmaceutical agents under Good Manufacturing Practice (GMP) conditions.
• Regulatory Submissions: Provides a certified standard for supporting drug master files (DMFs), investigational new drug (IND) applications, and new drug applications (NDAs).

Basic Information

Product Name	(+)-Pentazocine Mixed Agonist/Antagonist
CAS No.	64024-15-3
Molecular Formula	C19H27NO
Molecular Weight	285.43 g/mol
Synonyms	(+)-Pentazocine; (2R,6R,11R)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; Win 20,228; Fortral; Talwin; Sosegon; Pentazocine Lactate; Pentazocine Hydrochloride; Dextro-Pentazocine
EINECS	Contact for details

Quality Control

Our (+)-Pentazocine is manufactured and tested to meet stringent quality standards suitable for research and pharmaceutical development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to a robust quality management system and can supply material under GMP-grade conditions upon request to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (dextro isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.