Description

2-(Acetoacetylamino)Ethanethiol is a specialized organic compound featuring both acetoacetamide and thiol functional groups, making it a versatile building block for chemical synthesis. Its unique bifunctional structure allows it to act as a key intermediate in the creation of complex molecules, particularly in pharmaceutical and advanced material applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries who require a high-purity, reactive intermediate for coupling and derivatization reactions.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring thiol or acetoacetamide linkages.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators where its reactive groups enable specific bioactivity.
• Polymer Modification: Acts as a chain transfer agent or cross-linking monomer in the production of specialty polymers, enhancing material properties like adhesion and elasticity.
• Bioconjugation Reagent: Utilized in biochemical research for labeling proteins, peptides, and other biomolecules via its thiol-reactive site.
• Chemical Research & Development: A valuable tool for organic chemists exploring new synthetic pathways and creating novel heterocyclic compounds.
• Material Science: Employed in the surface functionalization of nanoparticles and the creation of self-assembled monolayers (SAMs).

Basic Information

Product Name	2-(Acetoacetylamino)Ethanethiol
CAS No.	63950-93-6
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	N-(2-Mercaptoethyl)acetoacetamide; 2-[(Acetoacetyl)amino]ethanethiol; Acetoacetamide, N-(2-mercaptoethyl)-; 2-(Acetoacetamido)ethanethiol; N-Acetoacetyl-2-aminoethanethiol; 2-Acetoacetamidoethanethiol; AAET; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-(Acetoacetylamino)Ethanethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and potential moisture absorption, the container must be kept sealed when not in use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.