Description

5-Bromo-8-Nitroisoquinoline is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of pharmaceuticals and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its nitro and bromo functional groups for structural diversification.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in academic and industrial R&D for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo substituent.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex nitro- and azo-based dyes and pigments.
• Ligand Synthesis: Utilized for the preparation of specialized chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	5-Bromo-8-Nitroisoquinoline
CAS No.	63927-23-1
Molecular Formula	C9H5BrN2O2
Molecular Weight	253.05 g/mol
Synonyms	8-Nitro-5-bromoisoquinoline; Isoquinoline, 5-bromo-8-nitro-; 5-Bromo-8-nitro-isoquinoline; 5-Bromo-8-nitro-isoquinoline; 5-Br-8-NO2-IQ
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Nitroisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.