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(2-Trimethylsilylethyl)Triphenylphosphonium Iodide CAS NO 63922-84-9


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CAS No.:63922-84-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Trimethylsilylethyl)Triphenylphosphonium Iodide is a specialized organosilicon phosphonium salt, a key reagent in advanced organic synthesis. Its value lies in its dual functionality, serving as a stable phosphonium ylide precursor for Wittig olefination reactions and as a silyl transfer agent. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require precise methods for constructing carbon-carbon double bonds and introducing silicon-protecting groups.

Application

  • Wittig Olefination Reagent: A crucial precursor for generating stabilized ylides to synthesize alkenes, particularly useful for creating sensitive or complex olefins in drug discovery and natural product synthesis.
  • Silylating Agent: Facilitates the introduction of the (2-trimethylsilyl)ethyl group, which can act as a protecting group for alcohols or carboxylic acids in multi-step synthetic sequences.
  • Pharmaceutical Intermediate Synthesis: Used in the construction of key molecular scaffolds for active pharmaceutical ingredients (APIs) and fine chemicals.
  • Material Science Research: Employed in the synthesis of novel organosilicon compounds and polymers with tailored properties.
  • Agrochemical Development: Applied in the synthesis of advanced intermediates for crop protection agents.
  • Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name (2-Trimethylsilylethyl)Triphenylphosphonium Iodide
CAS No. 63922-84-9
Molecular Formula C23H28IPSi
Molecular Weight 490.35 g/mol
Synonyms 2-(Trimethylsilyl)ethyltriphenylphosphonium Iodide; [(2-Trimethylsilyl)ethyl]triphenylphosphonium Iodide; (2-TMS-ethyl)triphenylphosphonium Iodide; (β-Trimethylsilylethyl)triphenylphosphonium Iodide; Triphenyl(2-trimethylsilylethyl)phosphonium Iodide; Phosphonium, (2-trimethylsilylethyl)triphenyl-, iodide; TMS-Et-PPh3 I; Silane, [[(iodotriphenylphosphoranylidene)ethyl]trimethyl-
EINECS Contact for details

Quality Control

Our (2-Trimethylsilylethyl)Triphenylphosphonium Iodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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