Description

3,5-Dibromo-4-Pyridinethiol is a halogenated pyridine derivative that serves as a versatile sulfur-containing heterocyclic building block. This compound is valued for its ability to introduce both bromine and thiol functional groups into molecular frameworks, enabling the synthesis of complex ligands, pharmaceuticals, and agrochemicals. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogen and sulfur motifs.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-withdrawing bromine substituents.
• Chemical Biology Probes: Utilized to create thiol-reactive probes or tags for studying protein interactions and cellular processes.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.

Basic Information

Product Name	3,5-Dibromo-4-Pyridinethiol
CAS No.	63905-95-3
Molecular Formula	C5H3Br2NS
Molecular Weight	268.96 g/mol
Synonyms	4-Pyridinethiol, 3,5-dibromo-; 3,5-Dibromopyridine-4-thiol; 3,5-Dibromo-4-mercaptopyridine; 4-Mercapto-3,5-dibromopyridine; 3,5-Dibromo-4-thiopyridinol
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-4-Pyridinethiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.