Description

1,2,3,4-Tetrahydro-3-Methyl-5H-Pyrido[3,2-B]Indole-5-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of complex pharmacologically active molecules, particularly within the pharmaceutical research and development sector. It is primarily needed by R&D chemists and process development scientists working on novel therapeutic agents, including central nervous system (CNS) drugs and other bioactive indole derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel drug candidates, particularly those targeting neurological pathways.
• Organic Synthesis Building Block: Used in the construction of complex polycyclic frameworks and heterocyclic systems for medicinal chemistry and material science applications.
• Research & Development (R&D): Essential for academic and industrial research programs focused on indole and tetrahydro-β-carboline chemistry.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Potential use in studying enzyme interactions and biochemical pathways related to its structural motif.

Basic Information

Product Name	1,2,3,4-Tetrahydro-3-Methyl-5H-Pyrido[3,2-B]Indole-5-Carboxylic Acid
CAS No.	63869-96-5
Molecular Formula	C₁₃H₁₄N₂O₂
Molecular Weight	230.26 g/mol
Synonyms	3-Methyl-1,2,3,4-tetrahydro-5H-pyrido[3,2-b]indole-5-carboxylic acid; 3-Methyl-1,2,3,4-tetrahydro-β-carboline-5-carboxylic acid; 3-Methyl-5-carboxy-1,2,3,4-tetrahydro-β-carboline; 5H-Pyrido[3,2-b]indole-5-carboxylic acid, 1,2,3,4-tetrahydro-3-methyl-; Tetrahydro-3-methyl-5H-pyrido[3,2-b]indole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-3-Methyl-5H-Pyrido[3,2-B]Indole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is compatible with strong acid/organic solvent environments but should be handled accordingly. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.