Description

4,5α-Epoxy-3-Hydroxy-17-Methyl-5β-Pentylmorphinan-6-One is a high-purity synthetic morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of specialized active pharmaceutical ingredients (APIs). It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutic agents within the central nervous system (CNS) domain.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex, target-specific active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control (HPLC, GC-MS) in pharmaceutical analysis to ensure product purity and identity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize pharmacological profiles for new drug candidates.
• Preclinical & Clinical Research: Serves as a starting material or metabolite standard in pharmacokinetic and pharmacodynamic studies during drug development phases.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis and neuropharmacology.

Basic Information

Product Name	4,5α-Epoxy-3-Hydroxy-17-Methyl-5β-Pentylmorphinan-6-One
CAS No.	63868-40-6
Molecular Formula	C24H33NO3
Molecular Weight	383.53 g/mol
Synonyms	6-Oxo-4,5α-epoxy-3-hydroxy-17-methyl-5β-pentylmorphinan; 5β-Pentyl-4,5α-epoxy-3-hydroxy-17-methylmorphinan-6-one; 17-Methyl-5β-pentyl-4,5α-epoxy-3-hydroxymorphinan-6-one; 4,5α-Epoxy-3-hydroxy-17-methyl-5β-pentylmorphinan-6-one; 63868-40-6; Pentylmorphinan derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 4,5α-Epoxy-3-Hydroxy-17-Methyl-5β-Pentylmorphinan-6-One is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC-MS, and NMR, to ensure identity, purity, and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development and commercial projects requiring adherence to cGMP, ISO, and other relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.