Description

(1R)-1β,2β-Dichloro-4β-[(E)-2-Chlorovinyl]-1-Methyl-5-Methylenecyclohexane CAS NO 63866-51-3 is a high-purity, stereochemically defined chlorinated cyclohexane derivative. This compound serves as a critical advanced intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its specific stereochemistry and functional groups enable precise molecular construction.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-infective agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its chlorinated structure can contribute to biological activity.
• Organic Synthesis Reagent: Serves as a versatile electrophile or scaffold in complex organic transformations, including cycloadditions and cross-coupling reactions, for academic and industrial laboratories.
• Material Science Precursor: Potential intermediate for synthesizing specialized monomers or ligands used in catalyst design and advanced polymer systems.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in the fine chemical industry.

Basic Information

Product Name	(1R)-1β,2β-Dichloro-4β-[(E)-2-Chlorovinyl]-1-Methyl-5-Methylenecyclohexane
CAS No.	63866-51-3
Molecular Formula	C10H13Cl3
Molecular Weight	239.57 g/mol
Synonyms	(1R,2R,4R)-1,2-Dichloro-4-[(E)-2-chloroethenyl]-1-methyl-5-methylenecyclohexane; (1R,2R,4R)-4-[(E)-2-Chlorovinyl]-1,2-dichloro-1-methyl-5-methylenecyclohexane; 1-Methyl-5-methylene-1,2-dichloro-4-[(E)-2-chlorovinyl]cyclohexane (stereospecific); NSC 338258; (1R,2R,4R)-rel-1,2-Dichloro-4-[(1E)-2-chloroethenyl]-1-methyl-5-methylenecyclohexane
EINECS	Contact for details

Quality Control

Every batch of (1R)-1β,2β-Dichloro-4β-[(E)-2-Chlorovinyl]-1-Methyl-5-Methylenecyclohexane is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and stereochemical integrity meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.