Description

2,4,5-Trimethylthiophene-3-Carboxaldehyde is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile aldehyde intermediate, enabling the construction of complex heterocyclic systems and functional materials. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise, high-quality intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides, where the thiophene core contributes to biological activity.
• Material Science: Serves as a monomer or functional unit in the production of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organocatalysts.
• Flavor & Fragrance Industry: Acts as a starting material for synthesizing sulfur-containing aroma compounds with unique sensory profiles.
• Dye and Pigment Manufacturing: Utilized as an intermediate for producing specialized heterocyclic dyes and pigments.

Basic Information

Product Name	2,4,5-Trimethylthiophene-3-Carboxaldehyde
CAS No.	63826-44-8
Molecular Formula	C9H12OS
Molecular Weight	168.26 g/mol
Synonyms	3-Formyl-2,4,5-trimethylthiophene; 2,4,5-Trimethyl-3-thiophenecarboxaldehyde; 2,4,5-Trimethylthiophene-3-carbaldehyde; 3-Aldehyde-2,4,5-trimethylthiophene; TMTCA; Trimethylthiophenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2,4,5-Trimethylthiophene-3-Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.