Description

1,2-Dimethyl-5-(Trifluoromethyl)-1H-Benzimidazole is a high-value, fluorinated benzimidazole derivative, a key structural motif in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used as a key precursor in developing advanced fungicides, herbicides, and insecticides, leveraging the bioactivity of the benzimidazole core.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology Probes: Employed in the design of enzyme inhibitors and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	1,2-Dimethyl-5-(Trifluoromethyl)-1H-Benzimidazole
CAS No.	63815-72-5
Molecular Formula	C10H9F3N2
Molecular Weight	214.19 g/mol
Synonyms	5-(Trifluoromethyl)-1,2-dimethyl-1H-benzimidazole; 1,2-Dimethyl-5-trifluoromethylbenzimidazole; 1H-Benzimidazole, 1,2-dimethyl-5-(trifluoromethyl)-; 5-Trifluoromethyl-1,2-dimethylbenzimidazole; 1,2-Dimethyl-5-(trifluoromethyl)benzimidazole; 63815-72-5; DTXSID60678420
EINECS	Contact for details

Quality Control

Our 1,2-Dimethyl-5-(Trifluoromethyl)-1H-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.