Description

6,7-Dimethoxy-1-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class, a privileged scaffold in medicinal chemistry. Its value lies in its role as a versatile and critical pharmaceutical intermediate for the research and development of active pharmaceutical ingredients (APIs). This compound is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Alkaloid Synthesis: Serves as a precursor in the synthesis of natural product analogs and complex alkaloid derivatives.
• Chemical Reference Standard: Employed as a high-purity standard in analytical testing and method development for quality control.
• Preclinical Development: Utilized in the production of compounds for pharmacological screening and toxicology studies.

Basic Information

Product Name	6,7-Dimethoxy-1-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	63768-20-7
Molecular Formula	C₁₇H₁₉NO₂
Molecular Weight	269.34 g/mol
Synonyms	1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-phenylisoquinoline; 1-Phenyl-6,7-dimethoxytetrahydroisoquinoline; 6,7-Dimethoxy-1-phenyl-THIQ; THIQ derivative 63768-20-7
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1-Phenyl-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.