Description

4,5α-Epoxy-3-Ethoxy-17-Methylmorphinan-8α-Ol is a high-purity synthetic organic compound belonging to the morphinan class, identified by CAS number 63732-72-9. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or reference standard in the synthesis of specialized active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, where precise chemical structure and high purity are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex pharmaceutical compounds, especially within the opioid and analgesic research domains.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing of related substances.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) and receptor binding affinities.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic Research: A valuable reagent for universities and research institutes conducting studies in medicinal chemistry and organic synthesis.

Basic Information

Product Name	4,5α-Epoxy-3-Ethoxy-17-Methylmorphinan-8α-Ol
CAS No.	63732-72-9
Molecular Formula	C20H27NO3
Molecular Weight	329.44 g/mol
Synonyms	3-Ethoxy-4,5α-epoxy-17-methylmorphinan-8α-ol; 8α-Hydroxy-3-ethoxy-4,5α-epoxy-17-methylmorphinan; 4,5α-Epoxy-3-ethoxy-17-methylmorphinan-8α-ol; 3-Ethoxy-17-methyl-4,5α-epoxymorphinan-8α-ol; 17-Methyl-3-ethoxy-4,5α-epoxymorphinan-8α-ol
EINECS	Contact for details

Quality Control

Every batch of 4,5α-Epoxy-3-Ethoxy-17-Methylmorphinan-8α-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.