Description

7,8-Didehydro-4,5α-Epoxy-17-Methyl-6α-Piperidinomorphinan-3-Ol is a complex morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical characterization of specialized opioid receptor ligands. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, medicinal chemistry, and the development of novel analgesic agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in drug development pipelines.
• Medicinal Chemistry Research: Serves as a key synthetic intermediate or precursor for the design and synthesis of new morphinan-based compounds with potential therapeutic activity.
• Neuropharmacological Studies: Employed in in vitro and in vivo research to study opioid receptor binding, function, and signal transduction pathways.
• Analytical Method Development: Critical for developing and calibrating sophisticated analytical techniques such as HPLC, LC-MS, and NMR for the detection and quantification of related substances.
• Impurity Profiling: Used to identify and quantify process-related impurities or degradation products in active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	7,8-Didehydro-4,5α-Epoxy-17-Methyl-6α-Piperidinomorphinan-3-Ol
CAS No.	63732-66-1
Molecular Formula	C23H28N2O2
Molecular Weight	364.48 g/mol
Synonyms	17-Methyl-6α-piperidino-4,5α-epoxymorphinan-3-ol; 4,5α-Epoxy-17-methyl-6α-piperidinomorphinan-3-ol; 6α-Piperidino-4,5α-epoxy-17-methylmorphinan-3-ol; 7,8-Didehydro-4,5α-epoxy-17-methyl-6α-piperidinomorphinan-3-ol; Noroxymorphone piperidine analog; Piperidinonormorphinan derivative
EINECS	Contact for details

Quality Control

Our 7,8-Didehydro-4,5α-Epoxy-17-Methyl-6α-Piperidinomorphinan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.