Description

(-)-3-Methoxy Butorphanol CAS NO 63730-48-3 is a high-purity, stereochemically defined chemical intermediate of significant interest in advanced pharmaceutical research and development. Its precise molecular configuration makes it a valuable building block for the synthesis of complex, biologically active compounds. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel analgesic and central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of analogs for biological screening and target validation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex organic molecules in pilot plant and commercial manufacturing.
• Academic Research: Utilized in university and institutional laboratories for studies in organic synthesis, pharmacology, and neurochemistry.

Basic Information

Product Name	(-)-3-Methoxy Butorphanol
CAS No.	63730-48-3
Molecular Formula	C21H29NO2
Molecular Weight	327.46 g/mol
Synonyms	(-)-3-Methoxybutorphanol; 17-(Cyclobutylmethyl)morphinan-3,14-diol, 3-methoxy-, (5α,6β)-; (5α,6β)-17-(Cyclobutylmethyl)-3-methoxymorphinan-14-ol; 3-Methoxybutorphanol; Butorphanol 3-Methyl Ether; Levomethadone analog intermediate
EINECS	Contact for details

Quality Control

Our (-)-3-Methoxy Butorphanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identification by spectroscopic methods (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.