Description

6,7-Didehydro-4,5α-Epoxy-3-Methoxy-8β-Phenoxymorphinan is a high-purity synthetic organic compound belonging to the morphinan class, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its complex, functionalized structure, which provides a versatile scaffold for the synthesis of specialized active pharmaceutical ingredients (APIs) and reference standards. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on developing and producing novel analgesic and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent opioid receptor ligands and other specialized therapeutic agents.
• Research & Development (R&D): Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new chemical entities with targeted pharmacological profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control, method development, and regulatory submissions in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies investigating receptor binding mechanisms and the biochemical pathways of morphinan-derived compounds.

Basic Information

Product Name	6,7-Didehydro-4,5α-Epoxy-3-Methoxy-8β-Phenoxymorphinan
CAS No.	63690-29-9
Molecular Formula	C24H25NO4
Molecular Weight	391.46 g/mol
Synonyms	8β-Phenoxy-6,7-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan; Phenoxymorphinan derivative; 6,7-Didehydro-4,5α-epoxy-3-methoxy-17-methyl-8β-phenoxymorphinan; 8β-Phenoxymorphinan intermediate; 17-Methyl-8β-phenoxy-6,7-didehydro-4,5α-epoxy-3-methoxymorphinan; 8β-Phenoxy-6,7-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan; 8β-Phenoxy-6,7-didehydro-4,5α-epoxy-3-methoxy-N-methylmorphinan
EINECS	Contact for details

Quality Control

Our 6,7-Didehydro-4,5α-Epoxy-3-Methoxy-8β-Phenoxymorphinan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.