Description

2-(1H-Benzimidazol-2-Yl)-4-Chloro-3-Oxobutanenitrile is a specialized organic intermediate featuring a benzimidazole core linked to a chloro-oxobutanenitrile moiety. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for developing advanced fungicides, herbicides, and plant growth regulators that leverage the benzimidazole pharmacophore.
• Material Science Research: Used in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing complex heterocyclic dyes and functional colorants.
• Biochemical Probe Development: Utilized in medicinal chemistry to create tool compounds for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2-(1H-Benzimidazol-2-Yl)-4-Chloro-3-Oxobutanenitrile
CAS No.	63572-67-8
Molecular Formula	C₁₁H₈ClN₃O
Molecular Weight	233.65 g/mol
Synonyms	4-Chloro-2-(1H-benzimidazol-2-yl)-3-oxobutanenitrile; 4-Chloro-3-oxo-2-(1H-benzimidazol-2-yl)butanenitrile; 2-(1H-Benzimidazol-2-yl)-4-chloro-3-oxobutyronitrile; 4-Chloro-2-(2-benzimidazolyl)-3-oxobutanenitrile; 63572-67-8; Butanenitrile, 4-chloro-2-(1H-benzimidazol-2-yl)-3-oxo-
EINECS	Contact for details

Quality Control

Our 2-(1H-Benzimidazol-2-Yl)-4-Chloro-3-Oxobutanenitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistent quality and batch-to-batch reproducibility. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.