Description

Exo-2-Bromo-5-Oxo-Bicyclo[2.2.1]heptane-Syn-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is critical for the synthesis of complex molecules, offering a versatile chiral building block for medicinal chemistry and process development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used as a building block for constructing constrained analogs and exploring structure-activity relationships (SAR) in early-stage drug discovery.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Asymmetric Synthesis: Utilized in reactions requiring specific stereochemical control due to its defined exo and syn configuration.
• Fine Chemical Production: Acts as a precursor for specialty chemicals used in agrochemicals and advanced material science.
• Academic & Contract Research: Supplied to universities and CROs for methodological development and synthetic studies.

Basic Information

Product Name	Exo-2-Bromo-5-Oxo-Bicyclo[2.2.1]heptane-Syn-7-Carboxylic Acid
CAS No.	63557-38-0
Molecular Formula	C8H7BrO3
Molecular Weight	231.04 g/mol
Synonyms	2-Bromo-5-oxobicyclo[2.2.1]heptane-7-carboxylic acid, exo-; (1S,2R,4S)-2-Bromo-5-oxobicyclo[2.2.1]heptane-7-carboxylic acid; 2-Bromo-5-norbornanone-7-carboxylic acid; 7-Carboxy-2-bromo-5-norbornanone; Bicyclo[2.2.1]heptane-7-carboxylic acid, 2-bromo-5-oxo-, (1S,2R,4S)-; 63557-38-0; exo-2-Bromo-5-oxonorbornane-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our Exo-2-Bromo-5-Oxo-Bicyclo[2.2.1]heptane-Syn-7-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the specified 99% purity standard and identity. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.