Description

L-Alanine-3,3,3-D3 is a stable isotope-labeled analog of the essential amino acid L-alanine, specifically deuterated at the three methyl hydrogens. This high-purity labeled compound is critical for advanced research requiring precise metabolic and pharmacokinetic tracing. It is primarily utilized by analytical chemists, pharmaceutical researchers, and life science professionals in metabolomics, proteomics, and drug development studies where internal standards are necessary for accurate quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative reference in LC-MS and GC-MS analyses for amino acid profiling in biological samples.
• Metabolic Pathway Tracing: Used in NMR and MS-based studies to investigate amino acid metabolism, protein synthesis, and turnover rates in cell cultures, tissues, and whole organisms.
• Pharmaceutical Research: Employed in the development and validation of bioanalytical methods for new drug candidates, ensuring accurate measurement of drug and metabolite levels.
• Nutritional Science Research: Facilitates studies on protein digestion, absorption, and utilization in humans and animals.
• Isotope Dilution Analysis: Provides high-accuracy results in clinical diagnostics and environmental analysis for alanine detection.
• Biochemical Reagent: Used in enzymatic assays and as a building block for synthesizing more complex deuterated peptides and biomolecules.

Basic Information

Product Name	L-Alanine-3,3,3-D3
CAS No.	63546-27-0
Molecular Formula	C3H4D3NO2
Molecular Weight	92.11 g/mol
Synonyms	(2S)-2-Aminopropanoic-3,3,3-d3 Acid; L-α-Alanine-3,3,3-d3; (S)-Alanine-3,3,3-d3; Deuterated L-Alanine; L-Alanine-d3; Alanine-3,3,3-d3; (S)-2-Aminopropionic-3,3,3-d3 Acid; Propanoic-3,3,3-d3 acid, 2-amino-, (S)-
EINECS	Contact for details

Quality Control

Our L-Alanine-3,3,3-D3 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity for research applications. Each batch is fully characterized by advanced spectroscopic and chromatographic techniques. Certificates of Analysis (COA) are provided, detailing parameters such as isotopic purity (D-enrichment), chemical purity, chiral purity, and specific analytical data (NMR, MS, HPLC). We support compliance with relevant GMP and ISO guidelines for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.