Description

(2,3,5,6-Tetrafluorophenyl)Maleimide is a highly functionalized, fluorinated maleimide derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the maleimide group combined with the electron-withdrawing and lipophilicity-enhancing properties of the tetrafluorophenyl substituent. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where it is used to create novel active ingredients and high-performance materials. CAS No. 63539-54-8.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and targeted therapy research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with improved environmental and efficacy profiles.
• Polymer Modification: Used as a cross-linking agent or comonomer to introduce fluorinated aromatic groups into polymers, enhancing thermal stability, chemical resistance, and surface properties.
• Material Science: Precursor for advanced organic electronic materials, including semiconductors and light-emitting diodes (OLEDs).
• Bioconjugation: Acts as a linker for attaching fluorophores, peptides, or other molecules to proteins and antibodies in diagnostic and therapeutic applications.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, particularly in cycloaddition and Michael addition reactions.

Basic Information

Product Name	(2,3,5,6-Tetrafluorophenyl)Maleimide
CAS No.	63539-54-8
Molecular Formula	C10H3F4NO2
Molecular Weight	245.13 g/mol
Synonyms	2,3,5,6-Tetrafluorophenylmaleimide; 1H-Pyrrole-2,5-dione, 1-(2,3,5,6-tetrafluorophenyl)-; Tetrafluorophenylmaleimide; 4-(2,3,5,6-Tetrafluorophenyl)-2,5-pyrroledione; N-(2,3,5,6-Tetrafluorophenyl)maleimide; TFP-Maleimide; Perfluorophenylmaleimide (common name for the tetrafluoro variant)
EINECS	Contact for details

Quality Control

Our (2,3,5,6-Tetrafluorophenyl)Maleimide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.