Description

4-Chloro-1-(5-Chlorothiophen-2-Yl)Butan-1-One is a high-purity chlorinated thiophene derivative, a crucial building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, serving as a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for R&D chemists and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring thiophene-based scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its chlorinated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials due to the thiophene moiety.
• Chemical Research & Development: A versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	4-Chloro-1-(5-Chlorothiophen-2-Yl)Butan-1-One
CAS No.	63490-84-6
Molecular Formula	C8H8Cl2OS
Molecular Weight	223.12 g/mol
Synonyms	1-(5-Chloro-2-thienyl)-4-chloro-1-butanone; 4-Chloro-1-(5-chloro-2-thienyl)-1-butanone; 4-Chloro-1-(5-chlorothiophen-2-yl)butan-1-one; 5-Chloro-2-(4-chlorobutyryl)thiophene; 2-(4-Chlorobutyryl)-5-chlorothiophene; 63490-84-6; Butan-1-one, 4-chloro-1-(5-chlorothiophen-2-yl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(5-Chlorothiophen-2-Yl)Butan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.