Description

Benzo[A]Pyrene-D12 is a deuterated internal standard of the polycyclic aromatic hydrocarbon (PAH) Benzo[a]pyrene, where twelve hydrogen atoms are replaced with deuterium. This compound is essential for ensuring analytical accuracy and reliability in quantitative mass spectrometry, providing a stable isotopic reference to correct for sample loss and instrument variability. It is a critical reagent for environmental monitoring, food safety testing, and toxicological research laboratories that require precise quantification of this potent carcinogen.

Application

• Internal Standard for GC-MS/LC-MS Analysis: Primary use as a quantitative reference standard for the accurate measurement of Benzo[a]pyrene in complex matrices.
• Environmental Analysis: Quantifying PAH contamination in soil, water, air particulate matter, and industrial waste for regulatory compliance and site remediation studies.
• Food Safety Testing: Detection and quantification of Benzo[a]pyrene in smoked foods, grilled meats, edible oils, and other foodstuffs to ensure compliance with international safety limits.
• Toxicology and Metabolic Studies: Used in research to track the metabolism, distribution, and DNA adduct formation of Benzo[a]pyrene in biological systems.
• Pharmaceutical Impurity Profiling: Potential use in method development for detecting and quantifying genotoxic impurities in active pharmaceutical ingredients (APIs).
• Occupational Health Monitoring: Calibrating equipment for measuring worker exposure to PAHs in industries like aluminum production, coke plants, and asphalt paving.
• Method Development and Validation: A key component in establishing and validating new analytical methods for PAH detection according to EPA, ISO, or other standardized protocols.
• Quality Control in Reference Material Production: Used in the preparation and certification of certified reference materials (CRMs) for PAH analysis.

Basic Information

Product Name	Benzo[A]Pyrene-D12
CAS No.	63466-71-7
Molecular Formula	C20D12
Molecular Weight	264.39 g/mol
Synonyms	Benzo[a]pyrene-d12; 3,4-Benzpyrene-d12; B[a]P-d12; 1,2-Benzopyrene-d12; 3,4-Benzopyrene-d12; Benzo(def)chrysene-d12; 3,4-Benzpyrene (ring-d12); Dibenz[a,h]anthracene-d12 (common misnomer, verify context); Deuterated Benzo[a]pyrene Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Benzo[A]Pyrene-D12 is manufactured and analyzed under strict quality systems to ensure the high purity and isotopic enrichment required for trace-level analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on purity, isotopic enrichment, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as indicated on the product label or COA. For long-term storage, keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline solid or solution
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥98% (Chemical Purity)
Isotopic Enrichment	≥98 atom % D
Isotopic Purity (MS)	≥99% (d12)
Solvent (if supplied as solution)	As specified (e.g., Acetonitrile, Toluene)
Concentration (if supplied as solution)	As specified (e.g., 100 µg/mL ± 5%)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.