Description

D-Phenylalaninol-D2 CAS NO 63386-43-6 is a deuterium-labeled derivative of phenylalaninol, a valuable chiral building block and intermediate. This isotopically labeled compound is essential for applications requiring precise molecular tracking and analysis, offering enhanced stability and specificity in research. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and analytical laboratories engaged in advanced synthesis, metabolic studies, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of deuterated drug candidates, where deuterium incorporation can improve metabolic stability and pharmacokinetic profiles.
• Metabolic Pathway Tracer: Used in mass spectrometry and NMR-based studies to trace and elucidate biological pathways and drug metabolism.
• Agrochemical Research: Serves as a building block in the synthesis of novel, isotopically labeled pesticides and herbicides for environmental fate studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in the synthesis of enantiomerically pure compounds for fine chemicals.
• Analytical Reference Standard: Used as an internal standard in quantitative LC-MS and GC-MS analysis to ensure accuracy and reproducibility in complex matrices.
• Biochemical Research: Applied in peptide mimetics and enzyme inhibitor studies where the deuterium label provides mechanistic insights.

Basic Information

Product Name	D-Phenylalaninol-D2
CAS No.	63386-43-6
Molecular Formula	C9H11D2NO
Molecular Weight	153.22 g/mol
Synonyms	(R)-2-Amino-3-phenyl-1-propanol-d2; (R)-2-Amino-3-phenylpropan-1-ol-d2; D-β-Phenylalaninol-d2; (R)-Phenylalaninol-d2; D-Phenylalaninol (deuterated); (2R)-2-Amino-3-phenylpropyl alcohol-d2; (R)-2-Amino-3-phenyl-1-propanol (α,β-d2)
EINECS	Contact for details

Quality Control

Our D-Phenylalaninol-D2 is produced under strict quality management protocols to ensure high chemical purity and isotopic enrichment. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity (by HPLC), isotopic purity (D-content), chiral purity, and residual solvent analysis. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.