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n-Methyl-9-Borabicyclo[3.3.1]Nonan-9-Amine CAS NO 63366-66-5
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CAS No.:63366-66-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Methyl-9-Borabicyclo[3.3.1]Nonan-9-Amine is a versatile organoboron reagent, specifically a chiral amine-borane complex, widely recognized for its utility in asymmetric synthesis. Its primary value lies in its role as a highly effective chiral reducing agent and catalyst precursor, enabling the production of enantiomerically pure compounds critical for advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), chiral ligands, and other high-value specialty chemicals.
Application
- Asymmetric Reduction: Employed as a chiral catalyst or stoichiometric reagent for the enantioselective reduction of ketones, imines, and other prochiral functional groups.
- Pharmaceutical Intermediate Synthesis: A key building block in the multi-step synthesis of complex, optically active drug molecules and bioactive compounds.
- Chiral Auxiliary and Ligand Preparation: Used to synthesize novel chiral ligands for transition metal catalysis or to introduce chiral amine functionalities.
- Agrochemical Research: Applied in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
- Material Science: Investigated for the preparation of boron-containing polymers or advanced materials with specific optical properties.
- Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and for scaling up chiral transformations.
Basic Information
| Item | Details |
|---|---|
| Product Name | n-Methyl-9-Borabicyclo[3.3.1]Nonan-9-Amine |
| CAS No. | 63366-66-5 |
| Molecular Formula | C9H18BN |
| Molecular Weight | 151.06 g/mol |
| Synonyms | 9-BBN-N-Methylamine; N-Methyl-9-BBN-amine; N-Methyl-9-borabicyclo[3.3.1]nonan-9-amine; Methylamine-9-BBN complex; (9-BBN)NMeH2; 9-Borabicyclo[3.3.1]nonane, 9-(methylamino)-; Chiral 9-BBN amine derivative |
| EINECS | Contact for details |
Quality Control
Every batch of n-Methyl-9-Borabicyclo[3.3.1]Nonan-9-Amine is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. Our quality assurance includes rigorous analytical testing, and a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and key impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.
Storage
Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or solution |
| Identification (IR) | Conforms to structure |
| Purity (HPLC/NMR) | ≥ 95.0% |
| Chiral Purity (ee) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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