Description

2-(1H-Indol-3-Ylsulfanyl)-Propionic Acid is a specialized sulfur-containing indole derivative, a key building block in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines the indole heterocycle with a propionic acid moiety via a thioether linkage, enabling the development of novel compounds with targeted biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel therapeutic agents, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging the bioactivity of the indole-thioether structure.
• Biochemical Probe Synthesis: Employed to create molecular probes for studying enzyme function and protein interactions in biochemical assays.
• Peptidomimetics: Acts as a non-natural amino acid analog for constructing peptide-like molecules with enhanced stability or specific binding properties.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with unique electronic or surface properties.

Basic Information

Product Name	2-(1H-Indol-3-Ylsulfanyl)-Propionic Acid
CAS No.	63321-71-1
Molecular Formula	C11H11NO2S
Molecular Weight	221.27 g/mol
Synonyms	3-[(2-Carboxyethyl)thio]-1H-indole; 2-(1H-Indol-3-ylthio)propanoic acid; 2-(Indol-3-ylsulfanyl)propionic acid; 3-(2-Carboxyethylthio)indole; 2-(3-Indolylthio)propionic acid; β-(3-Indolylthio)propionic acid; (1H-Indol-3-ylthio)propanoic acid
EINECS	Contact for details

Quality Control

Our 2-(1H-Indol-3-Ylsulfanyl)-Propionic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.