Description

Diethyl (1,3-Dithian-2-Yl)Phosphonate is a specialized organophosphorus compound that serves as a versatile building block in advanced organic synthesis. Its core value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective construction of complex carbon-carbon double bonds. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality reagents for synthesizing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly for constructing olefin linkages in a stereocontrolled manner.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators where specific alkene geometry is required for biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials that incorporate specific alkene functionalities.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for the synthesis of complex natural products and molecular scaffolds in research laboratories.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized phosphonate-based ligands used in catalysis.

Basic Information

Product Name	Diethyl (1,3-Dithian-2-Yl)Phosphonate
CAS No.	62999-73-9
Molecular Formula	C9H19O3PS2
Molecular Weight	270.35 g/mol
Synonyms	Diethyl (1,3-dithian-2-yl)phosphonate; (1,3-Dithian-2-yl)phosphonic Acid Diethyl Ester; 2-(Diethoxyphosphoryl)-1,3-dithiane; Diethyl 1,3-dithian-2-ylphosphonate; Phosphonic Acid, (1,3-Dithian-2-yl)-, Diethyl Ester; 1,3-Dithiane-2-phosphonic Acid Diethyl Ester; HWE Reagent (1,3-Dithiane based)
EINECS	Contact for details

Quality Control

Our Diethyl (1,3-Dithian-2-Yl)Phosphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay (purity), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and industrial-scale chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.