Description

(Formylmethyl)Triphenylphosphonium Chloride is a versatile and highly reactive organophosphorus reagent, primarily used as a key building block in organic synthesis. Its value lies in its role as a stabilized ylide precursor for the Wittig olefination reaction, enabling the efficient synthesis of α,β-unsaturated aldehydes and other valuable intermediates. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity reagents for complex molecule construction.

Application

• Wittig Reaction Reagent: A fundamental precursor for generating the stabilized (formylmethylene)triphenylphosphorane ylide, used to convert carbonyl compounds into α,β-unsaturated aldehydes (enal synthesis).
• Pharmaceutical Intermediate Synthesis: Employed in the construction of complex drug molecules, particularly those containing conjugated aldehyde functionalities for further derivatization.
• Agrochemical Active Ingredient Production: Used in the synthesis of certain herbicides, fungicides, and plant growth regulators that require specific alkene chains.
• Fine Chemical and Fragrance Manufacturing: Facilitates the synthesis of specific aldehydes and unsaturated compounds used in flavors, fragrances, and specialty chemicals.
• Material Science Research: Serves as a building block for creating organic ligands, polymers, or molecular components with specific electronic properties.
• Academic and R&D Laboratories: A critical reagent for methodological development in organic chemistry and for teaching advanced synthetic techniques.

Basic Information

Product Name	(Formylmethyl)Triphenylphosphonium Chloride
CAS No.	62942-43-2
Molecular Formula	C20H18ClOP
Molecular Weight	340.78 g/mol
Synonyms	(Chloromethyl)formyltriphenylphosphorane; (Formylmethyl)triphenylphosphonium chloride; Triphenyl(2-oxoethyl)phosphonium chloride; 2-Oxoethyltriphenylphosphonium chloride; (2-Oxoethyl)triphenylphosphonium chloride; (Carboxymethyl)triphenylphosphonium chloride (common misnomer); Formylmethyltriphenylphosphonium chloride; Witting reagent precursor for enal synthesis
EINECS	Contact for details

Quality Control

Our (Formylmethyl)Triphenylphosphonium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high chemical purity and consistent performance as a synthesis reagent. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.