Description

(1,2,3,4-Tetrahydro-Isoquinolin-3-Yl)-Methanol is a versatile heterocyclic building block and chiral intermediate of significant importance in synthetic organic chemistry. Its core structure is highly valued for constructing complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of various therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel pesticides and herbicides due to its bioactive isoquinoline scaffold.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Academic and R&D Laboratories: Fundamental building block for methodological studies in organic synthesis and medicinal chemistry.
• Fine Chemical Synthesis: Intermediate for producing dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	(1,2,3,4-Tetrahydro-Isoquinolin-3-Yl)-Methanol
CAS No.	62928-94-3
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	3-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-3-isoquinolinemethanol; 3-Isoquinolinemethanol, 1,2,3,4-tetrahydro-; (1,2,3,4-Tetrahydroisoquinolin-3-yl)methanol; THIQ-3-Methanol; 3-Hydroxymethyl-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (1,2,3,4-Tetrahydro-Isoquinolin-3-Yl)-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO standards for pharmaceutical-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.