Description

(R)-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)-Methanol is a chiral intermediate of significant importance in modern synthetic organic chemistry. Its value lies in its utility as a key building block for the synthesis of more complex, biologically active molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis laboratories for the development of novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to introduce stereochemical complexity.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of compound libraries for high-throughput screening.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals and advanced materials requiring high enantiopurity.

Basic Information

Product Name	(R)-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)-Methanol
CAS No.	62855-02-1
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydro-3-isoquinolinemethanol; (R)-3-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline; (R)-TIHM; (R)-TIQM; (R)-Tetrahydroisoquinoline-3-methanol; (3R)-1,2,3,4-Tetrahydroisoquinoline-3-methanol; (R)-(-)-1,2,3,4-Tetrahydro-3-isoquinolinemethanol
EINECS	Contact for details

Quality Control

Our (R)-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)-Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.