Description

5-[[3,4-Dihydro-6-Methoxy-7-(Phenylmethoxy)-1-Isoquinolinyl]Methyl]-2-(Phenylmethoxy)Phenylcarbonic Acid Ethyl Ester Hydrochloride is a high-purity synthetic organic compound, primarily utilized as a critical intermediate in advanced pharmaceutical research and development. Its complex molecular structure, featuring an isoquinoline core, makes it a valuable building block for synthesizing novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new drug molecules.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in studies investigating enzyme inhibition and receptor binding mechanisms.
• Custom Synthesis: A starting material for the custom manufacturing of specialized derivatives and analogs for client-specific R&D projects.

Basic Information

Product Name	5-[[3,4-Dihydro-6-Methoxy-7-(Phenylmethoxy)-1-Isoquinolinyl]Methyl]-2-(Phenylmethoxy)Phenylcarbonic Acid Ethyl Ester Hydrochloride
CAS No.	62744-14-3
Molecular Formula	C34H33NO6 · HCl
Molecular Weight	580.09 g/mol (Free base: 543.63 g/mol)
Synonyms	5-[(6-Methoxy-7-benzyloxy-3,4-dihydro-1-isoquinolinyl)methyl]-2-(benzyloxy)benzoic acid ethyl ester hydrochloride; Ethyl 5-[(6-methoxy-7-benzyloxy-3,4-dihydro-1-isoquinolinyl)methyl]-2-benzyloxybenzoate hydrochloride; 62744-14-3; Benzyloxy Isoquinoline Derivative Hydrochloride; 2-(Benzyloxy)-5-[(6-methoxy-7-[(phenylmethoxy)-3,4-dihydro-1-isoquinolinyl]methyl]benzoic Acid Ethyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our 5-[[3,4-Dihydro-6-Methoxy-7-(Phenylmethoxy)-1-Isoquinolinyl]Methyl]-2-(Phenylmethoxy)Phenylcarbonic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.