Description

2-Propanol, 1-[(1,1-Dimethylethyl)Amino]-3-[(2-Methyl-1H-Indol-4-Yl)Oxy]-, Benzoate (Ester), (S)- is a high-purity, chiral synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its specific stereochemistry and functional groups, which make it a critical building block for creating complex, biologically active molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or oncology targets.
• Process Chemistry: Used in route scouting and optimization for the scalable synthesis of complex drug candidates.
• Asymmetric Synthesis: Serves as a precursor or reagent in stereoselective chemical transformations to introduce specific chiral centers.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and modify the biological activity of lead compounds.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) engaged in custom synthesis projects for pharmaceutical clients.

Basic Information

Product Name	2-Propanol, 1-[(1,1-Dimethylethyl)Amino]-3-[(2-Methyl-1H-Indol-4-Yl)Oxy]-, Benzoate (Ester), (S)-
CAS No.	62697-41-0
Molecular Formula	C24H30N2O3
Molecular Weight	394.51 g/mol
Synonyms	(S)-1-(tert-Butylamino)-3-((2-methyl-1H-indol-4-yl)oxy)propan-2-yl benzoate; Labetalol Impurity; Labetalol Related Compound; 1-[(1,1-Dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol benzoate (ester), (S)-; (S)-1-(tert-Butylamino)-3-(2-methyl-1H-indol-4-yloxy)-2-propanol benzoate; Benzoic acid, (S)-1-[(1,1-dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines where applicable for pharmaceutical ingredients. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and chiral assay, NMR, and MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes to ensure consistency and reliability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.