Description

Progabide is a high-purity pharmaceutical intermediate and research chemical with significant importance in the development of neuroactive compounds. Its primary value lies in its role as a precursor and reference standard for GABAergic agents, which are critical in neurological and psychiatric research. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers focused on developing treatments for central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced GABA (γ-aminobutyric acid) receptor agonists and related neuropharmaceuticals.
• Neurological Research: Used as a reference standard and active compound in preclinical studies investigating epilepsy, anxiety, and other CNS conditions.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structure for the development and scale-up of novel therapeutic agents targeting neurotransmitter systems.
• Biochemical Research: Employed in studies of GABA receptor binding, function, and modulation to understand neurological pathways and drug mechanisms.
• Quality Control & Analytical Standards: Provides a certified reference material for HPLC, LC-MS, and NMR methods to ensure the purity and identity of related drug substances.

Basic Information

Product Name	Progabide
CAS No.	62666-20-0
Molecular Formula	C₁₇H₁₆FN₃O₂
Molecular Weight	313.33 g/mol
Synonyms	4-[[(4-Fluorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]butanamide; SL 76 002; Gabrene; Progabidum; 4-[[(4-Fluorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]butyramide; (4-Fluorobenzylideneamino)-5-fluoro-2-hydroxybutyranilide
EINECS	Contact for details

Quality Control

Our Progabide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.