Description

1H-Benzimidazole-2-Acetonitrile,α-Formyl-(9Ci) is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both a benzimidazole core and a reactive formyl-acetonitrile moiety, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors, antiviral agents, and anti-parasitic compounds.
• Agrochemical Synthesis: Serves as a critical building block for developing new generations of fungicides, herbicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized N-heterocyclic carbene (NHC) precursors and other chelating ligands for catalytic applications.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) due to its electron-rich and coordinating properties.
• Dye and Pigment Chemistry: Acts as an intermediate for creating advanced colorants and fluorescent markers with specific photophysical characteristics.

Basic Information

Product Name	1H-Benzimidazole-2-Acetonitrile,α-Formyl-(9Ci)
CAS No.	62591-10-0
Molecular Formula	C₁₀H₇N₃O
Molecular Weight	185.18 g/mol
Synonyms	2-Formyl-1H-benzimidazole-2-acetonitrile; α-Formyl-1H-benzimidazole-2-acetonitrile; (1H-Benzimidazol-2-yl)(oxo)acetonitrile; 2-Cyano-2-(1H-benzimidazol-2-yl)ethanal; 2-(Cyanomethyl)-1H-benzimidazole-1-carboxaldehyde (tautomer); 2-(1H-Benzimidazol-2-yl)-2-oxoacetonitrile; 2-Benzimidazoleacetonitrile, α-formyl-
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-2-Acetonitrile,α-Formyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic and should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.