Description

7-[4-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Butyl]Theophyline is a specialized xanthine derivative with a complex molecular structure designed for targeted pharmacological activity. This compound matters for its potential as a key intermediate in the synthesis of advanced pharmaceutical agents, particularly those targeting respiratory and cardiovascular systems. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to develop new therapeutic entities and reference standards.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of novel adenosine receptor antagonists and bronchodilators.
• Biochemical Research: Used as a reference standard and active agent in studies of phosphodiesterase (PDE) inhibition and related cellular signaling pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development of new chemical entities for treating asthma, chronic obstructive pulmonary disease (COPD), and other inflammatory conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex organic molecules.
• Academic Research: Utilized in university and institutional labs for pharmacological and medicinal chemistry research programs.

Basic Information

Product Name	7-[4-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Butyl]Theophyline
CAS No.	62401-94-9
Molecular Formula	C19H25N5O5
Molecular Weight	403.43 g/mol
Synonyms	7-[4-[[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino]butyl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-8-one; 7-(4-{[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino}butyl)theophylline; Denbufylline Impurity; Denbufylline Related Compound A; 1,3-Dimethyl-7-[4-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]butyl]-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 7-[4-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Butyl]Theophyline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with stringent standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.