Description

1-Acetyl-5-Bromo-7-Nitroindoline is a high-purity, multi-functional indoline derivative, serving as a critical advanced intermediate in complex organic syntheses. Its unique molecular structure, featuring bromo and nitro substituents, makes it an essential building block for constructing novel heterocyclic compounds with targeted properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indole-based drug candidates, particularly for central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated nitro-indoline scaffold.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors and photoactive polymers.
• Dye & Pigment Chemistry: Acts as an intermediate for synthesizing complex, light-fast organic dyes and pigments.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and cross-coupling reactions.
• Custom Synthesis: A versatile starting material for custom synthesis projects requiring specific functionalization of the indoline core.

Basic Information

Product Name	1-Acetyl-5-Bromo-7-Nitroindoline
CAS No.	62368-07-4
Molecular Formula	C10H9BrN2O3
Molecular Weight	285.10 g/mol
Synonyms	5-Bromo-7-nitro-1-acetylindoline; 1-Acetyl-5-bromo-7-nitro-2,3-dihydro-1H-indole; 5-Bromo-7-nitroindoline-1-acetamide (related); N-(5-Bromo-7-nitro-2,3-dihydro-1H-indol-1-yl)ethanone; 2,3-Dihydro-5-bromo-7-nitro-1H-indole-1-acetamide (related); 62368-07-4; 1H-Indole, 2,3-dihydro-5-bromo-7-nitro-, 1-acetyl-
EINECS	Contact for details

Quality Control

Our 1-Acetyl-5-Bromo-7-Nitroindoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored in a dark environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.