Description

3-Iodo-Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive iodine substituent and ester functionality, which enable precise molecular construction in complex chemical environments. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-inflammatory applications.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science: Serves as a monomer or building block for conductive polymers, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Functional Dye Synthesis: Employed in the creation of advanced dyes and pigments with specific optical properties.
• Chemical Biology Probes: Used to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-Iodo-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	62353-77-9
Molecular Formula	C6H5IO2S
Molecular Weight	268.07 g/mol
Synonyms	Methyl 3-iodothiophene-2-carboxylate; 3-Iodo-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-iodo-, methyl ester; Methyl 3-iodo-2-thiophenecarboxylate; 3-Iodothiophene-2-carboxylic acid methyl ester; 3-Iodo-2-methoxycarbonylthiophene
EINECS	Contact for details

Quality Control

Our 3-Iodo-Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.