Description

1-(5-Chloro-2-Nitrophenyl)-3,4-Dihydro-6,7-Dimethoxyisoquinoline is a specialized heterocyclic organic compound that serves as a crucial advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring a fused isoquinoline core with chloro and nitro substituents, makes it a valuable building block for constructing complex pharmacologically active molecules. This high-purity intermediate is primarily sought by research institutions and pharmaceutical development companies engaged in the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging its halogenated aromatic structure.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a core structure for developing electron-transport or host materials in OLED displays and lighting due to its fused ring system.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized, high-performance dyes and pigments where nitro and methoxy groups contribute to color and stability.
• Academic and Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry, cross-coupling reactions, and nitro group transformations.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(5-Chloro-2-Nitrophenyl)-3,4-Dihydro-6,7-Dimethoxyisoquinoline
CAS No.	62206-13-7
Molecular Formula	C₁₇H₁₅ClN₂O₄
Molecular Weight	346.77 g/mol
Synonyms	6,7-Dimethoxy-1-(5-chloro-2-nitrophenyl)-3,4-dihydroisoquinoline; 1-(5-Chloro-2-nitrophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline; 62206-13-7; 1-(5-Chloro-2-nitrophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 5-Chloro-2-nitrophenyl-6,7-dimethoxy-3,4-dihydroisoquinoline; 6,7-Dimethoxy-1-(5'-chloro-2'-nitrophenyl)-3,4-dihydroisoquinoline
EINECS	Contact for details

Quality Control

Our production of 1-(5-Chloro-2-Nitrophenyl)-3,4-Dihydro-6,7-Dimethoxyisoquinoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.