Description

(S)-4,5,5-Triphenyl-2-Oxazolidinone is a high-purity, chiral oxazolidinone derivative widely utilized as a versatile chiral auxiliary and building block in asymmetric synthesis. Its well-defined stereochemistry and robust structure make it invaluable for controlling enantioselectivity in critical chemical transformations. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise stereochemical outcomes are paramount for product efficacy and regulatory approval.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Employed to induce enantioselectivity in aldol, alkylation, Diels-Alder, and Michael addition reactions.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides with improved selectivity and environmental profiles.
• Catalyst and Ligand Development: Acts as a scaffold for creating novel chiral catalysts and ligands for homogeneous catalysis.
• Academic & Industrial R&D: A fundamental tool in organic chemistry laboratories for method development and stereochemical studies.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(S)-4,5,5-Triphenyl-2-Oxazolidinone
CAS No.	62183-23-7
Molecular Formula	C21H17NO2
Molecular Weight	315.37 g/mol
Synonyms	(S)-4,5,5-Triphenyl-2-oxazolidinone; (S)-(-)-4,5,5-Triphenyl-2-oxazolidinone; (4S)-4,5,5-Triphenyl-1,3-oxazolidin-2-one; (S)-Triphenyloxazolidinone; Evans Auxiliary (S)-Triphenyl variant; (S)-N-Triphenylmethyl-2-oxazolidinone; (S)-α,α,α-Triphenyl-2-oxazolidinemethanol
EINECS	Contact for details

Quality Control

Our (S)-4,5,5-Triphenyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to guarantee traceability and consistency for your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.