Description

8-Chloro-3A, 6-Epoxy-1,2,3A, 6-Tetrahydro-3-Methyl-6-Phenyl-3H-Imidazo [1, 2-A][1,4]Benzodiazepine-1,2-Dione is a high-purity, complex heterocyclic compound of significant interest in advanced pharmaceutical research and development. This specialized benzodiazepine derivative serves as a critical pharmacological intermediate and a key scaffold for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in neuroscience and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine analogs and other central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating ligand-receptor interactions, particularly with GABAA receptors.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).
• Academic Research: A valuable compound for universities and institutes conducting research in organic synthesis and drug discovery.

Basic Information

Product Name	8-Chloro-3A, 6-Epoxy-1,2,3A, 6-Tetrahydro-3-Methyl-6-Phenyl-3H-Imidazo [1, 2-A][1,4]Benzodiazepine-1,2-Dione
CAS No.	62167-11-7
Molecular Formula	C19H14ClN3O3
Molecular Weight	367.79 g/mol
Synonyms	8-Chloro-3a,6-epoxy-1,2,3a,6-tetrahydro-3-methyl-6-phenyl-3H-imidazo[1,2-a][1,4]benzodiazepine-1,2-dione; 8-Chloro-6-phenyl-3-methyl-1,2,3a,6-tetrahydro-3a,6-epoxyimidazo[1,2-a][1,4]benzodiazepine-1,2-dione; Imidazobenzodiazepinone derivative; 62167-11-7; 8-Chloro-3-methyl-6-phenyl-3a,6-epoxy-1,2,3a,6-tetrahydro-3H-imidazo[1,2-a][1,4]benzodiazepine-1,2-dione
EINECS	Contact for details

Quality Control

Our 8-Chloro-3A, 6-Epoxy-1,2,3A, 6-Tetrahydro-3-Methyl-6-Phenyl-3H-Imidazo [1, 2-A][1,4]Benzodiazepine-1,2-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.