Description

Octadecanoic-18,18,18-D3 Acid is a deuterium-labeled isotopologue of stearic acid, where three terminal hydrogen atoms are replaced by deuterium. This high-purity, stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily required by research laboratories, pharmaceutical developers, and analytical service providers working in metabolomics, lipidomics, pharmacokinetic studies, and stable isotope tracer research.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the precise quantification of stearic acid and related fatty acids in LC-MS and GC-MS analyses.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer to study lipid metabolism, biosynthesis, and degradation in biological systems.
• Pharmaceutical Research: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of lipid-based drug compounds.
• Clinical Diagnostics: Facilitates accurate measurement of fatty acid profiles in plasma or tissue samples for disease biomarker research.
• Nutritional Science: Applied in research investigating fatty acid absorption, distribution, and metabolic fate.
• Quality Control Reference: Acts as a certified reference material (CRM) for calibrating analytical instruments and validating methods.

Basic Information

Product Name	Octadecanoic-18,18,18-D3 Acid
CAS No.	62163-39-7
Molecular Formula	C18H33D3O2
Molecular Weight	285.49 g/mol
Synonyms	Stearic-18,18,18-d3 Acid; Octadecanoic-d3 Acid; Deuterated Stearic Acid; [18,18,18-2H3]Octadecanoic Acid; 18,18,18-Trideuteriooctadecanoic Acid; Isotopic Stearic Acid; Fatty Acid-d3; NMR Standard Stearic Acid-d3
EINECS	Contact for details

Quality Control

Our deuterium-labeled Octadecanoic Acid is manufactured under strict quality protocols to ensure exceptional isotopic purity and chemical stability, meeting the exacting requirements of analytical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity (by HPLC/GC), and identity confirmation (by NMR and MS). We adhere to cGMP principles where applicable for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (by 1H NMR or MS)
Chemical Purity (HPLC / GC)	≥ 98.0%
Melting Point	67 - 71 °C
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.