Description

Benzothiophene-3-Carboxylic Acid, 4,5,6,7-Tetrahydro-2-(2,5-Dioxo-3-Pyrrolin-1-yl) is a high-value heterocyclic building block that combines a tetrahydrobenzothiophene scaffold with a maleimide functional group. This compound is critical for advanced organic synthesis, offering a versatile handle for conjugation and cycloaddition reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or requiring specific heterocyclic frameworks.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique fused-ring structure for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, coatings, and resins with tailored thermal or mechanical properties.
• Bioconjugation Chemistry: The maleimide moiety is utilized for selective thiol-Michael addition, making it valuable for labeling proteins, peptides, and antibodies in biotech applications.
• Organic Synthesis Building Block: Employed in Diels-Alder and other cycloaddition reactions to construct complex polycyclic structures for academic and industrial research.

Basic Information

Item	Detail
Product Name	Benzothiophene-3-Carboxylic Acid, 4,5,6,7-Tetrahydro-2-(2,5-Dioxo-3-Pyrrolin-1-yl)
CAS No.	62159-47-1
Molecular Formula	C13H13NO4S
Molecular Weight	279.31 g/mol
Synonyms	1-(4,5,6,7-Tetrahydro-1-benzothiophen-3-ylcarbonyl)-1H-pyrrole-2,5-dione; 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic Acid; 4,5,6,7-Tetrahydro-2-(2,5-dioxo-3-pyrrolin-1-yl)benzothiophene-3-carboxylic Acid; Maleimide-substituted Tetrahydrobenzothiophene-3-carboxylic Acid; N-(4,5,6,7-Tetrahydrobenzo[b]thiophene-3-carbonyl)maleimide; Tetrahydrobenzothiophene maleimide carboxylic acid; 62159-47-1; 1H-Pyrrole-2,5-dione, 1-[(4,5,6,7-tetrahydro-3-benzothienyl)carbonyl]-
EINECS	Contact for details

Quality Control

Our Benzothiophene-3-Carboxylic Acid, 4,5,6,7-Tetrahydro-2-(2,5-Dioxo-3-Pyrrolin-1-yl) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.