Description

6-Fluoroserotonin is a fluorinated derivative of the essential neurotransmitter serotonin, distinguished by the substitution of a fluorine atom at the 6-position of the indole ring. This structural modification makes it a critical biochemical research tool and a valuable intermediate in the development of novel pharmaceuticals and diagnostic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies engaged in neuroscience, receptor binding studies, and the synthesis of serotonergic compounds.

Application

• Neuroscience Research: Acts as a selective ligand and probe for studying serotonin (5-HT) receptor subtypes, their distribution, and function.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential therapeutic agents targeting the central nervous system.
• Biochemical Assay Development: Used in the development and validation of high-throughput screening (HTS) assays for drug discovery programs.
• Metabolic Pathway Studies: Employed to investigate the metabolism and transport mechanisms of fluorinated neurotransmitters.
• Reference Standard: Utilized as an analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and research quantification.
• Radioligand Precursor: A potential precursor for the synthesis of radiolabeled (e.g., 18F) compounds for Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	6-Fluoroserotonin
CAS No.	62105-96-8
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	6-Fluoro-5-hydroxytryptamine; 5-Hydroxy-6-fluorotryptamine; 6-Fluoro-5-HT; 6-F-5HT; 6-Fluorosertonin; 6-Fluoroserotonin creatinine sulfate complex; 6-Fluoroserotonin hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Fluoroserotonin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.